Blood Dialysis: How Hemodialysis Works, Who Needs It and What to Expect

Learn how blood dialysis works, when hemodialysis is recommended, how dialysis removes waste and fluid from the blood and what patients should know before treatment.

13 Aug, 2026

When the kidneys are no longer able to remove enough waste and excess fluid from the body, blood dialysis, commonly known as hemodialysis, can help perform some of these essential functions.

Hemodialysis uses a dialysis machine and a specialized filter called a dialyzer to clean the blood. It can be used for people with advanced chronic kidney disease and for some patients who develop severe acute kidney injury.

Dialysis is not automatically required whenever kidney function is reduced. A nephrologist determines whether it is appropriate based on the patient's symptoms, laboratory results, fluid status, kidney function and overall medical condition.

At Prabhakar Bhurke Clinic, Dr. Sandip Prabhakar Bhurke, super specialist nephrologist and transplant physician, provides specialist care for kidney disease, kidney failure and dialysis management.

What is blood dialysis?

During hemodialysis, a patient's blood is circulated through a dialyzer outside the body.

The dialyzer contains a semipermeable membrane that allows certain waste products and excess substances to move out of the blood into dialysis fluid.

The cleaned blood is then returned to the patient's body.

In simple terms, the process helps replace some of the filtering work normally performed by healthy kidneys.

Why is blood dialysis needed?

Healthy kidneys remove waste products, regulate fluid and help maintain appropriate levels of electrolytes and acids in the body.

Severe kidney dysfunction can result in the accumulation of:

  • Urea and other waste products
  • Excess fluid
  • Potassium
  • Acids
  • Other substances that the kidneys normally regulate

When these problems become severe and cannot be adequately controlled with medical treatment, dialysis may be required.

Does every kidney patient need dialysis?

No.

A person can have significantly reduced kidney function without immediately requiring dialysis.

The decision to begin dialysis is based on the overall clinical picture, rather than kidney function alone.

Doctors may consider:

  • Symptoms caused by kidney failure
  • Persistent fluid overload
  • Difficult-to-control potassium abnormalities
  • Significant acid buildup
  • Nutritional deterioration
  • Reduced urine output
  • Response to other treatments
  • Overall health and quality of life

How does blood dialysis work?

A typical hemodialysis treatment involves several stages.

1. Accessing the bloodstream

Blood must safely travel from the body to the dialysis machine and back.

Common types of vascular access include:

  • Arteriovenous fistula
  • Arteriovenous graft
  • Dialysis catheter

The access method depends on the patient's circumstances and whether dialysis is expected to be temporary or long term.

2. Blood travels to the dialyzer

Blood passes through tubing into the dialysis machine.

The dialyzer acts as an artificial filtering system.

3. Waste and excess fluid are removed

Inside the dialyzer, waste products and excess substances move from the blood into the dialysis fluid through the membrane.

The amount of fluid removed is carefully prescribed.

4. Filtered blood returns to the body

After passing through the dialyzer, the treated blood returns to the patient's bloodstream.

The process continues for the prescribed duration.

What is a dialysis machine?

A dialysis machine controls and monitors several aspects of hemodialysis.

Depending on the system and prescription, it helps manage:

  • Blood flow
  • Dialysis fluid flow
  • Fluid removal
  • Pressure monitoring
  • Safety alarms
  • Treatment duration

The dialysis prescription is individualized by the treating medical team.

How long does blood dialysis take?

The duration and frequency of hemodialysis vary between patients.

Many people receiving maintenance hemodialysis undergo treatment several times per week, with each session lasting several hours.

However, schedules can differ depending on:

  • Remaining kidney function
  • Body size
  • Fluid accumulation
  • Laboratory results
  • Dialysis access
  • Medical condition
  • The prescribed dialysis dose

Patients should follow the schedule recommended by their nephrology team.

What is a dialysis access and why is it important?

Dialysis access provides a reliable route for blood to leave and return to the body.

Arteriovenous fistula

An AV fistula connects an artery and vein, usually in the arm.

It is often preferred for long-term hemodialysis when suitable because it can provide durable access and generally has a lower infection risk than a catheter.

Arteriovenous graft

An AV graft uses a synthetic or biological material to connect an artery and vein.

It may be considered when a patient's veins are not suitable for creation of a fistula.

Dialysis catheter

A catheter is inserted into a large vein.

Catheters may be used when dialysis needs to begin urgently or when another access is not yet available.

Long-term catheter use can carry a higher risk of infection and other complications, so access planning is important.

What happens before a dialysis session?

The healthcare team may assess:

  • Blood pressure
  • Weight
  • Fluid status
  • Symptoms
  • Vascular access
  • Recent laboratory results
  • Medication requirements

Weight measurements before and after dialysis can help estimate how much excess fluid needs to be removed.

What happens after blood dialysis?

After treatment, the dialysis team may check the patient's:

  • Blood pressure
  • Weight
  • Vascular access
  • General condition

Some people feel tired after dialysis, while others return to their normal activities relatively quickly.

Individual experiences vary.

Possible side effects of hemodialysis

Some patients may experience:

  • Low blood pressure
  • Muscle cramps
  • Fatigue
  • Headache
  • Nausea
  • Dizziness
  • Itching
  • Problems related to vascular access

Not every patient experiences these effects.

If symptoms occur repeatedly during or after dialysis, the dialysis team should be informed because the treatment prescription or other factors may need review.

What complications can affect dialysis access?

Vascular access requires regular care.

Potential problems include:

  • Infection
  • Bleeding
  • Clotting
  • Reduced blood flow
  • Narrowing of the access
  • Loss of access function

Patients should monitor their access as instructed by their healthcare team.

For an AV fistula or graft, the care team may teach patients how to check for the normal vibration or "thrill" of the access.

What should a blood dialysis patient eat?

There is no single diet suitable for every dialysis patient.

Dietary requirements may involve individualized control of:

  • Sodium
  • Potassium
  • Phosphorus
  • Protein
  • Fluid
  • Calories

The diet may also need to account for diabetes, heart disease, nutritional status and laboratory results.

A renal dietitian or nephrologist can provide a personalized dietary plan.

Why is fluid control important during dialysis?

When kidney function is severely reduced, the body may not remove fluid efficiently.

Excess fluid can contribute to:

  • Swelling
  • High blood pressure
  • Breathlessness
  • Heart strain

Patients receiving maintenance dialysis may therefore be given an individualized fluid allowance.

Fluid recommendations should never be copied from another dialysis patient because requirements differ.

Can dialysis completely replace the kidneys?

No.

Hemodialysis performs some of the functions of healthy kidneys, particularly removing waste products and excess fluid and helping regulate certain electrolytes.

Healthy kidneys perform additional hormonal and metabolic functions that dialysis does not fully reproduce.

For this reason, appropriate medical management and monitoring remain important even when a patient is receiving regular dialysis.

Is kidney transplant an alternative to blood dialysis?

For medically suitable patients with irreversible kidney failure, kidney transplantation may be an alternative form of kidney replacement therapy.

A successful transplant can provide functioning kidney tissue that performs many of the functions of a healthy kidney.

Not every patient is suitable for transplantation, and evaluation is required to determine eligibility.

Some patients may also receive dialysis while waiting for a transplant.

Can a person with acute kidney injury need blood dialysis?

Yes.

Some patients with severe acute kidney injury may temporarily require dialysis.

If kidney function subsequently recovers sufficiently, dialysis may no longer be necessary.

This differs from established end stage kidney disease, where long-term kidney replacement therapy may be required unless transplantation or another appropriate treatment changes the situation.

How can dialysis patients protect their health?

Patients receiving regular hemodialysis should:

  • Attend dialysis sessions according to their prescribed schedule
  • Take medicines exactly as directed
  • Follow individualized dietary and fluid recommendations
  • Protect their vascular access
  • Attend scheduled blood tests
  • Report unusual symptoms promptly
  • Maintain appropriate vaccination and infection-prevention measures
  • Keep regular nephrology appointments

Missing dialysis sessions without medical advice can lead to serious complications.

When should a dialysis patient seek urgent medical care?

Seek prompt medical attention for symptoms such as:

  • Severe breathlessness
  • Chest pain
  • Fainting
  • Severe weakness
  • Confusion
  • High fever or chills
  • Significant bleeding from dialysis access
  • Sudden loss of fistula or graft flow
  • Severe swelling
  • Persistent vomiting

These symptoms should not be ignored.

Blood dialysis care at Prabhakar Bhurke Clinic

At Prabhakar Bhurke Clinic, Dr. Sandip Prabhakar Bhurke provides specialist nephrology care for patients requiring evaluation and management of advanced kidney disease.

Depending on individual needs, care may include:

  • Assessment of kidney function
  • Evaluation of dialysis requirements
  • Hemodialysis management
  • Vascular access monitoring
  • Management of dialysis-related complications
  • Anemia management
  • Electrolyte and mineral management
  • Fluid and blood pressure management
  • Nutritional guidance
  • Kidney transplant evaluation when appropriate
  • Long term kidney care

The goal is to create a treatment plan based on the patient's medical condition, dialysis requirements and long-term health needs.

Frequently Asked Questions

Is blood dialysis painful?

The dialysis procedure itself is not usually described as painful, although inserting needles for an AV fistula or graft can cause temporary discomfort. Some patients may experience side effects such as cramps or low blood pressure during treatment.

How many times a week is blood dialysis required?

Maintenance hemodialysis is commonly performed several times a week, but the exact frequency and duration are determined by the treating nephrologist.

Can dialysis patients drink water?

Fluid intake is often individualized for people receiving dialysis. The appropriate amount depends on factors such as urine output, fluid gain between treatments, heart health and dialysis prescription.

Can kidneys recover after dialysis?

In some cases of acute kidney injury, kidney function may recover enough for dialysis to be discontinued. In established irreversible kidney failure, long-term dialysis or transplantation may be required.

What happens if a dialysis patient misses a session?

Missing a dialysis treatment can allow excess fluid, potassium and waste products to accumulate. Patients should contact their dialysis team rather than independently changing their treatment schedule.

Conclusion

Blood dialysis, or hemodialysis, is an established form of kidney replacement therapy that helps remove waste products and excess fluid from the blood when kidney function is severely impaired.

Successful dialysis care involves more than the dialysis machine itself. Appropriate vascular access, medication management, nutrition, fluid control, laboratory monitoring and regular nephrology follow-up are all important parts of treatment.

For patients with advanced kidney disease, understanding dialysis options early can make treatment planning easier and help support long-term kidney care.

For specialist evaluation and dialysis management, patients can consult Dr. Sandip Prabhakar Bhurke at Prabhakar Bhurke Clinic.

Medical Disclaimer

This article is provided for general educational and informational purposes only. It does not constitute medical advice, diagnosis or treatment. The need for dialysis, dialysis frequency, treatment duration, fluid intake, diet and medication requirements vary from patient to patient and must be determined by a qualified nephrologist. Do not start, stop or change dialysis, medicines or dietary restrictions without professional medical guidance. Patients experiencing severe breathlessness, chest pain, confusion, fainting, high fever, significant bleeding or other rapidly worsening symptoms should seek urgent medical attention. For individualized evaluation and treatment, consult Dr. Sandip Prabhakar Bhurke or another qualified healthcare professional.

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