Kidney Infection and Kidney Stones: Symptoms, Complications, Treatment and When It Becomes an Emergency

Kidney infection and kidney stones can occur together and may cause fever, flank pain, urinary symptoms and obstruction. Learn the warning signs, tests, treatment options and when urgent care is needed.

9 Oct, 2026

Kidney stones and urinary tract infections are different conditions, but they can occur together.

A kidney stone is a hard deposit formed from minerals and salts in urine. A kidney infection, also called pyelonephritis when it affects the kidney tissue, usually develops when bacteria travel through the urinary tract and reach one or both kidneys.

A stone may interfere with the normal flow of urine. When urine becomes trapped behind an obstruction, bacteria may be harder to clear, increasing the risk of serious infection. Certain stones, particularly infection-associated stones, may also be linked to recurrent urinary infections.

The most important concern is a stone that blocks urine drainage while an infection is present. This combination can become life-threatening and requires urgent medical assessment. The European Association of Urology identifies an infected, obstructed kidney as a urological emergency. citeturn619575search0

At Prabhakar Bhurke Clinic, Dr. Sandip Prabhakar Bhurke, super specialist nephrologist and transplant physician, provides evaluation and kidney care for patients with kidney-function abnormalities and related complications. When a stone requires a procedure, coordination with a urologist may be necessary.

How to Recognize a Kidney Stone With an Infection

A kidney stone may cause no symptoms, or it may produce pain when it moves or obstructs urine flow. An infection can add symptoms that require more urgent attention.

Possible symptoms include:

  • Pain in the back, side or flank

  • Fever or chills

  • Burning or pain during urination

  • Frequent or urgent urination

  • Cloudy or unusually strong-smelling urine

  • Blood in the urine

  • Nausea or vomiting

  • Feeling unusually weak or unwell

  • Reduced urine output when obstruction is present

Fever or chills with suspected kidney stones should never be ignored, especially when accompanied by flank pain, vomiting or reduced urine output. These findings may indicate infection with obstruction and require emergency evaluation. citeturn619575search0

Not every person with a kidney infection develops all these symptoms, and not every stone causes pain.

Kidney Stone Pain or Kidney Infection Pain: What Is the Difference?

The symptoms can overlap, so they cannot always be distinguished at home.

Feature Kidney stone Kidney infection
Pain May cause sudden, severe flank pain that comes in waves May cause persistent pain in the back or side
Fever and chills Not typical of an uncomplicated stone Important warning signs
Burning urination Can occur, especially with a lower urinary tract stone Common
Blood in urine Can occur Can also occur
Nausea or vomiting May accompany severe pain May occur with infection
Urinary obstruction Possible Can occur when a stone or another problem blocks drainage

A person can have both conditions at the same time. Symptoms alone cannot reliably determine whether urine flow is blocked or how severe the infection is.

Why Is an Infected, Blocked Kidney Dangerous?

When a stone blocks urine drainage, pressure can build up in the urinary collecting system. If bacteria are present, infection may worsen despite taking antibiotics alone because the obstruction remains unresolved.

Potential complications include:

  • Severe kidney infection

  • Infection spreading into the bloodstream

  • Sepsis

  • Acute kidney injury

  • Deterioration of kidney function

  • Serious illness requiring hospitalization

A blocked and infected urinary system needs urgent treatment. Doctors may first drain the kidney using a ureteral stent or a nephrostomy tube and begin appropriate antibiotics. Definitive stone removal is generally postponed until the infection has been controlled. citeturn619575search0

What Causes Kidney Stones and Recurrent Urinary Infections?

Several factors can contribute to stones, infections or both.

Urinary Obstruction

A stone lodged in the ureter can prevent urine from draining normally. Other causes of obstruction may also increase the risk of infection.

Infection-Associated Stones

Some stones, including struvite stones, can develop in association with particular urinary bacteria. These stones may become large or recur if the infection and stone burden are not adequately addressed.

Incomplete Stone Clearance

Residual fragments can sometimes contribute to ongoing symptoms, obstruction or recurrence, depending on the stone type and location.

Recurrent Urinary Infections

Repeated infections may prompt doctors to investigate stones, urinary tract abnormalities, incomplete bladder emptying or other contributing conditions.

Other Risk Factors

Diabetes, urinary tract abnormalities, previous stones, catheter use and certain medical conditions can influence infection risk or complicate treatment.

Identifying the reason for recurrent infections is important because antibiotics alone may not address a persistent structural problem.

How Do Doctors Diagnose Kidney Infection and Kidney Stones?

The evaluation aims to establish whether an infection is present, locate any stone, determine whether urine flow is obstructed and assess kidney function.

1. Urine Tests and Urine Culture

Urinalysis can identify findings such as white blood cells, blood or other abnormalities.

A urine culture helps identify bacteria and determine which antibiotics are likely to be effective. Culture results are particularly important when a kidney infection is suspected.

2. Blood Tests

Depending on the patient's condition, tests may include:

  • Serum creatinine and eGFR

  • Complete blood count

  • Electrolytes

  • Inflammatory markers

  • Blood cultures when a severe infection or sepsis is suspected

These tests help assess infection severity and whether kidney function has been affected.

3. Ultrasound

Ultrasound can identify many stones and signs of urinary tract dilation. It is often useful when obstruction needs to be assessed.

4. CT Scan

A CT scan may be recommended when more detailed information about stone size, location, obstruction or complications is required. The choice of imaging depends on the patient's condition, pregnancy status and other clinical factors.

Guidelines recommend imaging when obstruction or complicated infection is a concern, with the urgency and type of scan determined by the clinical situation. citeturn619575search7

How Is Kidney Infection With Stones Treated?

Treatment depends on whether the stone is obstructing urine flow, how severe the infection is, kidney function and the patient's overall condition.

Antibiotics for Bacterial Infection

A kidney infection generally requires appropriate antibiotics. The choice depends on the suspected or identified bacteria, culture results, allergies, kidney function, illness severity and local resistance patterns.

Severe infections may require hospital treatment and intravenous antibiotics.

Do not take leftover antibiotics or use a prescription from someone else. An antibiotic that is unsuitable for the bacteria or the patient's kidney function may fail to treat the infection adequately.

Urgent Drainage When a Stone Blocks Urine Flow

If an infected kidney is obstructed, urgent drainage may be required. Common options include:

  • Ureteral stent: a tube placed through the urinary tract to help urine drain from the kidney into the bladder.

  • Percutaneous nephrostomy: a drainage tube placed through the skin directly into the kidney.

The treating team chooses the method according to the patient's condition and available expertise. Antibiotics and drainage are started urgently when indicated. Definitive stone removal is usually delayed until the infection is controlled. citeturn619575search0

Stone Removal After Infection Control

Once the infection has been treated and the patient is stable, the stone may be managed according to its size, location and characteristics.

Possible procedures include:

  • Ureteroscopy with laser lithotripsy: an instrument reaches the stone through the urinary tract, and laser energy breaks it into smaller fragments.

  • Shock wave lithotripsy (SWL or ESWL): externally generated shock waves break selected stones into fragments.

  • Percutaneous nephrolithotomy (PCNL): a small access tract into the kidney allows removal of larger or complex stones.

Not every stone needs a procedure. Small, uncomplicated stones may sometimes pass naturally, but a stone associated with infection or obstruction needs careful specialist assessment. Treatment is selected according to imaging, kidney function and the patient's clinical condition. citeturn619575search5

Can Antibiotics Alone Treat an Infected Kidney Stone?

Sometimes antibiotics are sufficient for an infection when there is no significant obstruction and the patient is otherwise stable. However, antibiotics alone may not be enough when an infected stone blocks urine drainage.

In that situation, urgent drainage may be required in addition to antibiotics. Delaying treatment can allow the infection to worsen.

A clinician must determine whether obstruction is present rather than relying only on pain severity or temporary improvement after medication.

Can a Kidney Stone Damage Kidney Function?

A stone does not automatically cause permanent kidney damage. However, prolonged obstruction, severe infection or repeated complications can impair kidney function.

Doctors may monitor:

  • Creatinine and eGFR

  • Urine output

  • Imaging findings

  • Infection markers

  • Recovery after treatment

Prompt treatment can reduce the risk of complications. The likelihood of recovery depends on the duration and severity of obstruction, the infection and the patient's underlying kidney health.

What Should You Do While Waiting for Medical Assessment?

If you suspect a kidney infection with a stone, arrange prompt medical evaluation. Do not attempt to manage a possible obstructed infection with home remedies alone.

While following medical advice:

  • Take prescribed medicines exactly as directed.

  • Do not use leftover antibiotics.

  • Do not force large quantities of water to try to push a stone through.

  • Ask a clinician or pharmacist before taking painkillers, particularly if you have kidney disease, dehydration or reduced urine output.

  • Seek emergency care if fever, chills, severe pain, vomiting, confusion or reduced urine output develops.

If you have fever or chills with suspected stone-related obstruction, do not wait for a routine appointment.

How Can You Reduce the Risk of Future Stones and Infections?

Prevention depends on the stone type, urinary anatomy and the reason infections occur.

A doctor may recommend:

  • Stone analysis when a stone is passed or removed

  • Follow-up imaging when indicated

  • Appropriate fluid intake based on kidney and heart health

  • Reducing excessive dietary sodium

  • Stone-specific dietary advice

  • Evaluation of recurrent urinary infections

  • Management of diabetes and other relevant conditions

  • Further testing for recurrent or complicated stones

Some patients benefit from metabolic evaluation to understand why stones are forming. People with kidney failure, heart failure or prescribed fluid restrictions should not increase fluid intake without medical advice.

Kidney and Stone Care at Prabhakar Bhurke Clinic

At Prabhakar Bhurke Clinic, Dr. Sandip Prabhakar Bhurke, super specialist nephrologist and transplant physician, provides individualized kidney evaluation for patients with abnormal kidney function and complications associated with urinary tract conditions.

Depending on the clinical situation, assessment may include:

  • Review of creatinine and eGFR

  • Urine testing and infection-related investigations

  • Assessment of kidney function during acute illness

  • Review of ultrasound or CT reports

  • Evaluation of urinary obstruction and related kidney risks

  • Management of associated kidney disease

  • Follow-up after an episode of acute kidney injury

  • Coordination with urology or hospital teams when drainage or stone-removal procedures are required

The appropriate care pathway depends on whether infection, obstruction, kidney injury or another condition is present.

Frequently Asked Questions

Can kidney stones cause a kidney infection?

Stones can contribute to infection when they obstruct urine flow. Certain types of stones are also associated with urinary bacteria. However, not every kidney stone causes an infection.

What are the symptoms of a kidney infection with stones?

Symptoms may include flank pain, fever, chills, burning urination, nausea, vomiting or blood in urine. Fever or chills with suspected urinary obstruction requires urgent medical assessment.

Is an infected kidney stone an emergency?

An infected, obstructed kidney is a urological emergency. Treatment may require immediate antibiotics and drainage with a ureteral stent or nephrostomy tube. citeturn619575search0

Can a kidney infection go away without antibiotics?

A bacterial kidney infection generally requires appropriate medical treatment. Do not rely on home remedies or delay assessment when a kidney infection is suspected.

Will removing the stone stop recurrent kidney infections?

It may help when the stone is contributing to obstruction or infection, but recurrence also depends on the bacteria, urinary anatomy and other risk factors. Follow-up evaluation may be needed.

Can kidney stones cause high creatinine?

They can if they significantly obstruct urine drainage, particularly when both kidneys are affected or the patient has a single functioning kidney. Infection, dehydration and other illnesses can also affect creatinine.

Which doctor should treat kidney infection and kidney stones?

A nephrologist evaluates kidney function and medical kidney conditions, while a urologist commonly manages stone-related procedures and urinary obstruction. Some patients need coordinated care from both specialists.

Conclusion

Kidney infection and kidney stones can become a serious combination when a stone blocks the normal flow of urine. Symptoms may include flank pain, urinary discomfort, blood in urine, fever and chills. Because these symptoms can overlap with other conditions, medical assessment and appropriate testing are essential.

Treatment may involve antibiotics, blood and urine tests, imaging, urgent drainage of an obstructed infected kidney and stone removal after the infection is controlled. The right approach depends on the patient's condition, kidney function and the stone's location.

If you suspect a kidney infection with a stone, especially if you have fever, chills, severe pain, vomiting or reduced urine output, seek urgent medical attention rather than waiting for symptoms to settle.

For kidney-function assessment and individualized nephrology care, consult Dr. Sandip Prabhakar Bhurke at Prabhakar Bhurke Clinic.

Medical Disclaimer

This article is for general educational and informational purposes only and does not replace medical diagnosis, treatment or personalized advice. Kidney stones and kidney infections can occur together, and an infected urinary tract obstruction can be life-threatening. Fever, chills, severe flank pain, persistent vomiting, confusion or very little or no urine may require emergency care. Do not self-prescribe antibiotics, change prescribed medicines or attempt to force a stone to pass by drinking excessive amounts of water. Treatment may require antibiotics, urgent drainage and later stone removal, depending on the diagnosis. Consult a qualified healthcare professional for individualized care and seek emergency attention if serious symptoms occur.

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