Main Cause of Kidney Stones: Why They Form, Risk Factors, Symptoms and Prevention

Discover the main cause of kidney stones, how minerals form stones in the urinary tract, major risk factors, symptoms, testing, treatment and prevention tips.

25 Sep, 2026

The main cause of kidney stones is an imbalance in the substances dissolved in urine. When urine becomes too concentrated with certain stone-forming minerals and compounds, crystals can develop. These crystals may gradually grow into stones.

Common stone-forming substances include:

  • Calcium

  • Oxalate

  • Uric acid

  • Phosphate

  • Cystine in people with certain inherited conditions

A low urine volume can make stone formation more likely because substances become more concentrated.

However, kidney stones usually develop because of a combination of factors rather than one single cause.

At Prabhakar Bhurke Clinic, Dr. Sandip Prabhakar Bhurke, super specialist nephrologist and transplant physician, provides individualized evaluation for patients with kidney stones, recurrent stone formation and related kidney problems.

How Do Kidney Stones Form?

Urine contains water along with minerals and other dissolved substances.

Under normal circumstances, these substances remain dissolved and leave the body through urine. When their concentration becomes sufficiently high, crystals may form.

Over time, crystals can:

  1. Develop in concentrated urine.

  2. Stick together or grow.

  3. Remain within the kidney.

  4. Increase in size.

  5. Move into the ureter.

  6. Cause pain or urinary obstruction.

Not every kidney stone causes symptoms. Some remain in the kidney and are discovered incidentally during an ultrasound or other imaging examination.

The Most Common Type: Calcium Stones

Most kidney stones are calcium-based stones, with calcium oxalate being particularly common.

This does not necessarily mean that eating normal amounts of calcium causes stones.

Stone formation is influenced by several factors, including:

  • Urinary calcium

  • Urinary oxalate

  • Urine volume

  • Urinary citrate

  • Sodium intake

  • Dietary pattern

  • Metabolic conditions

  • Genetics

Reducing dietary calcium excessively without medical advice may not be beneficial and can sometimes increase oxalate absorption.

Why Does Dehydration Cause Kidney Stones?

Low urine volume is one of the important risk factors for kidney stone formation.

When a person does not consume enough fluid or loses substantial fluid through:

  • Sweating

  • Fever

  • Vomiting

  • Diarrhea

  • Heavy physical activity

urine becomes more concentrated.

Concentrated urine makes it easier for stone-forming substances to reach levels at which crystals can develop.

Adequate fluid intake can therefore play an important role in preventing many types of kidney stones.

However, people with advanced kidney disease, heart failure or prescribed fluid restrictions should follow individualized medical advice rather than deliberately increasing fluid intake.

Can Diet Be the Main Cause of Kidney Stones?

Diet can significantly influence stone risk.

Factors that may increase risk in susceptible individuals include:

  • High sodium intake

  • Excessive intake of certain animal proteins

  • High consumption of sugar-sweetened beverages

  • Low fluid intake

  • Excessive intake of oxalate-rich foods in specific situations

  • Inadequate dietary calcium in some individuals

The appropriate diet depends on the type of stone and the person's urine chemistry.

There is no single kidney-stone diet that is ideal for everyone.

How Does Salt Increase Kidney Stone Risk?

A high-sodium diet can increase the amount of calcium excreted in urine.

Higher urinary calcium can contribute to calcium stone formation in susceptible people.

Reducing excessive salt intake may therefore be an important part of kidney stone prevention.

Common sources of excess sodium include:

  • Packaged snacks

  • Pickles

  • Processed foods

  • Instant meals

  • Restaurant foods

  • Processed meats

  • Salty sauces and condiments

What Is the Connection Between Oxalate and Kidney Stones?

Oxalate can combine with calcium in the urine and contribute to calcium oxalate stone formation.

Foods containing significant amounts of oxalate include certain:

  • Leafy vegetables

  • Nuts

  • Seeds

  • Chocolate

  • Tea

  • Other plant foods

This does not mean everyone should avoid these foods.

For people with calcium oxalate stones, dietary advice should be based on the individual's stone history and urine testing. Maintaining an appropriate intake of dietary calcium can also be important.

Can High Uric Acid Cause Kidney Stones?

Yes.

Uric acid stones can develop when urine contains excessive uric acid and is often too acidic.

Factors associated with uric acid stone formation can include:

  • High uric acid production

  • Certain dietary patterns

  • Obesity and metabolic conditions

  • Gout

  • Persistently acidic urine

  • Low urine volume

Treatment and prevention may involve increasing appropriate fluid intake, dietary changes and, in selected patients, medicines that alter uric acid production or urine chemistry.

Can Genetics Cause Kidney Stones?

Yes.

Some people are genetically predisposed to developing stones.

Inherited conditions can cause unusual stone types or recurrent stone formation.

Examples include cystinuria, an inherited disorder that can lead to cystine stones.

A strong family history of kidney stones can also increase a person's likelihood of developing them.

People with recurrent stones, childhood stones or a strong family history may benefit from metabolic evaluation.

Can Obesity Increase the Risk of Kidney Stones?

Higher body weight and metabolic abnormalities can be associated with increased kidney stone risk.

Obesity can influence:

  • Urine chemistry

  • Uric acid metabolism

  • Urine acidity

  • Dietary habits

  • Insulin resistance

Maintaining a healthy weight through sustainable lifestyle changes may support both kidney and metabolic health.

Can Certain Medical Conditions Cause Kidney Stones?

Several medical conditions can increase stone risk.

These may include:

  • Gout

  • Hyperparathyroidism

  • Certain bowel diseases

  • Conditions causing chronic diarrhea

  • Metabolic disorders

  • Recurrent urinary infections

  • Some inherited diseases

People with recurrent stones may need evaluation for an underlying metabolic or medical cause.

Can Medicines Cause Kidney Stones?

Certain medicines can increase the risk of stones or contribute to crystal formation in susceptible individuals.

The risk depends on the specific medication, dose, duration and individual health factors.

Tell your doctor about all medicines and supplements you take if you develop recurrent kidney stones.

Do not discontinue a prescribed medicine without professional advice.

What Are the Symptoms of Kidney Stones?

A kidney stone may cause no symptoms if it remains in the kidney.

When a stone moves into the ureter, symptoms can include:

  • Severe side or flank pain

  • Pain spreading toward the lower abdomen or groin

  • Pain that comes in waves

  • Nausea

  • Vomiting

  • Blood in urine

  • Burning while urinating

  • Frequent urge to urinate

Symptoms depend on the stone's size, location and whether it is obstructing urine flow.

Can Kidney Stones Cause Back Pain?

Yes.

A stone can cause pain in the flank or back, particularly when it obstructs urine flow.

However, back pain does not automatically mean that a person has a kidney stone. Muscular, spinal and other conditions can produce similar symptoms.

Imaging may be required when a stone is suspected.

How Are Kidney Stones Diagnosed?

Evaluation may involve:

Urine Testing

Urine tests can identify:

  • Blood

  • Infection

  • Crystals

  • pH abnormalities

  • Other urinary changes

Blood Tests

Depending on the situation, doctors may check:

  • Kidney function

  • Calcium

  • Uric acid

  • Electrolytes

  • Other metabolic markers

Imaging

Ultrasound or CT imaging may help determine:

  • Stone size

  • Stone location

  • Number of stones

  • Urinary obstruction

  • Kidney swelling

Stone Analysis

If a stone is passed or removed, laboratory analysis can identify its composition.

Knowing the stone type can help guide future prevention.

Why Do Some People Keep Getting Kidney Stones?

Recurrent kidney stones may occur when the underlying risk factor remains untreated.

Possible reasons include:

  • Persistently low urine volume

  • High urinary calcium

  • High urinary oxalate

  • Low urinary citrate

  • High uric acid

  • Acidic urine

  • High sodium intake

  • Certain medical conditions

  • Genetic predisposition

A 24-hour urine metabolic evaluation may be recommended for selected patients with recurrent or high-risk stones.

How Can You Prevent Kidney Stones?

Prevention depends on the type of stone and individual risk factors.

General measures may include:

Maintain Adequate Fluid Intake

Increasing urine volume can reduce the concentration of stone-forming substances.

The amount of fluid needed varies from person to person.

Limit Excess Salt

Reducing excessive sodium can help lower urinary calcium in susceptible individuals.

Maintain Appropriate Dietary Calcium

Avoid unnecessarily eliminating calcium from the diet unless specifically advised.

Moderate Animal Protein

Some people with recurrent stones may benefit from avoiding excessive intake of animal protein.

Maintain a Healthy Weight

Weight management can support metabolic and urinary health.

Follow Stone-Specific Advice

A person with calcium oxalate stones may receive different dietary recommendations from someone with uric acid stones.

Does Drinking More Water Prevent Kidney Stones?

Adequate hydration can substantially reduce the risk of many kidney stones by increasing urine volume.

The goal is not simply to drink as much water as possible. Fluid needs should be individualized.

People with certain heart or kidney conditions may have fluid restrictions.

When Should You See a Kidney Specialist?

Specialist evaluation may be useful when you have:

  • Recurrent kidney stones

  • Multiple stones

  • Stones at a young age

  • A strong family history

  • Abnormal kidney-function tests

  • Bilateral stones

  • Urinary obstruction

  • Frequent urinary infections

  • Difficult-to-control metabolic risk factors

A nephrologist can assess metabolic risk factors and help develop a long-term prevention strategy.

Depending on the stone's size and location, a urologist may also be involved when a procedure is required.

When Is a Kidney Stone an Emergency?

Seek urgent medical attention if a suspected kidney stone is accompanied by:

  • Fever or chills

  • Severe or uncontrolled pain

  • Persistent vomiting

  • Very little or no urine

  • Significant weakness

  • Fainting

  • Known urinary obstruction

  • A single functioning kidney with suspected obstruction

A blocked urinary system combined with infection can become a serious medical emergency.

Kidney Stone Evaluation at Prabhakar Bhurke Clinic

At Prabhakar Bhurke Clinic, Dr. Sandip Prabhakar Bhurke, super specialist nephrologist and transplant physician, provides individualized evaluation for patients with kidney stones and recurrent stone formation.

Assessment may include:

  • Review of previous stone episodes

  • Kidney-function testing

  • Urine examination

  • Metabolic evaluation

  • Review of imaging

  • Assessment of dietary and lifestyle risk factors

  • Evaluation for recurrent stone causes

  • Prevention planning

  • Coordination with appropriate procedural specialists when stone removal is required

The objective is not only to manage the current stone but also to identify factors that may contribute to future stone formation.

Frequently Asked Questions

What is the main cause of kidney stones?

The main mechanism is the formation of crystals when urine becomes concentrated with stone-forming substances. Low urine volume, dietary factors, metabolic conditions, genetics and certain medicines can contribute.

Does drinking less water cause kidney stones?

Low fluid intake can reduce urine volume and make urine more concentrated, increasing the risk of crystal formation.

Is calcium the main cause of kidney stones?

Calcium-based stones are the most common type, but normal dietary calcium is not necessarily the cause. Stone formation depends on the balance of calcium, oxalate, citrate, urine volume and other factors.

Can high uric acid cause kidney stones?

Yes. High urinary uric acid combined with acidic, concentrated urine can contribute to uric acid stone formation.

Why do kidney stones keep coming back?

Recurrent stones may result from persistent metabolic abnormalities, low urine volume, dietary factors, genetics or an underlying medical condition. A metabolic evaluation can help identify preventable risk factors.

Can kidney stones be prevented permanently?

Recurrence cannot always be eliminated, but identifying the stone type and correcting modifiable risk factors can substantially reduce the likelihood of future stones in many people.

Conclusion

The main cause of kidney stones is the formation and growth of crystals in urine when stone-forming substances become sufficiently concentrated. Dehydration and low urine volume are important contributors, while calcium metabolism, oxalate, uric acid, diet, genetics, medications and certain medical conditions can further influence risk.

Because different stones have different causes, prevention should not rely on a single home remedy or generic diet. Stone analysis, urine testing, blood tests and metabolic evaluation can help identify the factors responsible for recurrent stone formation.

If you experience repeated kidney stones, urinary obstruction, abnormal kidney-function results or severe stone-related symptoms, specialist evaluation can help guide appropriate treatment and prevention.

For individualized kidney and stone-related care, consult Dr. Sandip Prabhakar Bhurke at Prabhakar Bhurke Clinic.

Medical Disclaimer

This article is intended for general educational and informational purposes only and does not constitute medical advice, diagnosis or treatment. Kidney stones have multiple possible causes, and prevention depends on the stone type, urine chemistry, kidney function, diet and individual medical history. Do not make major dietary changes, restrict calcium, increase fluid intake excessively or start supplements or medicines without professional guidance. Seek urgent medical attention for severe or uncontrolled pain, fever or chills with suspected kidney stones, persistent vomiting, very little or no urine, fainting or rapidly worsening symptoms. Consult Dr. Sandip Prabhakar Bhurke or another qualified healthcare professional for individualized evaluation and treatment.

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